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Search Results for " uterine fibroids "

11

Compounds

Cat No. Product Name Synonyms Targets
T27837 Linzagolix GNRH Receptor
Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharmaceutical and ObsEva for the treatment of uterine fibroids,...
T1048 Estradiol E2,17β-Estradiol,17β-Oestradiol,β-Estradiol Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility and maintenance of secondary sexual characteristics. Estradiol upregulates IL-6 expression through estrogen receptor be...
T35054 Vilaprisan BAY 1002670,BAY10-02670,BAY-1002670,BAY1002670,BAY-10-02670,BAY 10-02670 Progesterone Receptor
Vilaprisan (BAY 1002670) is a novel orally available and selective progesterone receptor modulator (SPRM) with antiproliferative activity against uterine fibroids (UF) and can be used for the study of uterine fibroids.
T13572 Cancer-Targeting Compound 1 Others
Cancer-Targeting Compound 1 can be used in the study of hormone-related cancers, including the treatment or prevention of fibroids, uterine leiomyomas, polycystic ovarian syndrome, or hormone-dependent Cancer, among othe...
T25742 Linzagolix choline GNRH Receptor
Linzagolix choline is an orally available non-peptide gonadotropin-releasing hormone (GnRH) antagonist. It can be used to study pain associated with uterine fibroids and endometriosis.
T32684 Leuprolide (1-3) Leuprorelin
Leuprolide (1-3) is a manufactured version of a hormone used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, and early puberty.
T21308 Histrelin Supprelin LA,Histrelin Acetate Others
Histrelin (Supprelin LA) acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. It is considered a GnRH agonist. Histrelin is used in the treatment of hormone-sensitive cancers of th...
T36859 C16 Globotriaosylceramide (d18:1/16:0) C16 Globotriaosylceramide (d18:1/16:0)
C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide . C16 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raj...
T71149 Triptorelin pamoate
Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituita...
T72990 BAY 1214784
BAY 1214784, a potent, selective, and orally active spiroindoline derivative compound, serves as an antagonist of the human gonadotropin-releasing hormone receptor (hGnRH-R). It notably reduces plasma luteinizing hormone...
T68525 Nafarelin acetate hydrate
Nafarelin is a gonadotropin-releasing hormone agonist (GnRH agonist) which acts as an analog of GnRH. Nafarelin increases the release of FSH and LH by the anterior pituitary, which in turn leads to an increase of estroge...
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